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Whilst very low-rely MBL not often progresses to CLL, higher-depend MBL progresses to CLL requiring therapy in a amount of 1% to 2% a year. Superior-rely MBL is distinguished from Rai 0 CLL depending on if the B-cell rely is earlier mentioned or under five × 109/L. While men and women with the two large-depend MBL and CLL Rai stage 0 are at improv